EDUCATION:
• Nantong Medical College,
Nantong, China
MD, 1978-1982.
• University of Paris XII,
Paris, France PhD,
1990–1992.

TRAINING:
• Nantong Medical College
Affiliated Hospital
Nantong, China;
Residency, 1983–1987.
• Medical College of Suzhou
University
Suzhou, China; PhD
Student 1987–1989.
• Unite 348 INSERM-Hospital,
Lariboisiere
Paris, France; Research
Fellowship
1989–1992.
• The Scripps Research
Institute, La Jolla, CA;
Research
Fellowship 1992–1995.
• Mount Sinai School of
Medicine (Jamaica)
Program (Queens
Hospital Center)
Jamaica, NY; Residency
1995–1998.
• University Hospitals of
Cleveland.

CLINICAL EXPERIENCE
(2001-2004)
• Case Western Reserve
University, Cleveland,
OH; Senior Instructor
• University Hospital of
Cleveland, Cleveland,
OH, Invasive
Cardiologist;
Cleveland, Cleveland
VAMC, Cleveland, OH;
Director,
Echocardiography Lab.

BOARD CERTIFICATIONS:
• American Board of Internal
Medicine 1999
• Cardiovascular Diseases
ABIM 2001
• Adult Comprehensive
Echocardiography
NBE 2001
• Nuclear Cardiology, ABNC
2002

SELECTED PUBLICATIONS:
• Chen YP, Djaffar I, Pidard
D, Steiner B, Cieutat AM,
Caen JP, Rosa JP. SER
752-Pro mutation in the
cytoplasmic Domain of
integrin subunit and
defective activation of
platelet integrin
(glycoprotein IIb-IIIa)
in a variant of
G lanzmann's
thrombasthenia.Proc
Nat'l Acad Sci USA
1992;89:
10169-10173.
• Ylanne J, Chen Y, O'Toole
TE, Loftus JC, Takada Y,
Ginsberg MH.
Distinct functions of
integrin and subunit
cytoplasmic domains in
cell spreading and
formation of focal
adhesion. J Cell Biol.
1993;122:223-233.
• Djaffer I, Chen YP
Creminon C,
Maclouf J, Cieutat AM,
Gayet O, Rosa JP.
A new alternative
transcript encodes a 60
kDa truncated form of
integrin beta 3. Biochem
J. 1994;300 (Pt 1):69-74.
• Chen YP, O'Toole TE,
Ylanne J, Rosa JP,
Ginsberg MH. A point
mutation in the integrin
beta 3 cytoplasmic
domain (S752- - >P)
impairs bidirectional
signaling through alpha
IIb beta 3 (platelet
glycoprotein IIb–IIIa).
Blood. 1994 Sept.
15;84:1857-65.
• Chen Y, Brennessel D,
Walters J, Johnson M,
Rosner F, Raza M. Human
Immunodeficiency virus
associated pericardial
effusion: report of 40
cases and review of the
literature. Am Heart J.
1999; 137(3):516-21.
• Chen Y, Bressessel D,
Johnson M, Rosner F.
Pericardial effusion is
acquired
immunodeficiency
disease.
Arch Intern Med.
2000; 160:2397-8.